Recent advancements in technology have significantly impacted the drug development process. Increasingly advanced and powerful tools have shifted the focus of primary drug activation as well as which diseases are gaining attention. Rare Diseases Rare diseases have become a greater interest to manufacturers due to scientific advancements and regulatory incentives. The Orphan Drug Act has included incentives such as extended exclusivity periods, tax credits, and waiving of FDA fees, leading to a large number of drug approvals focused on rare diseases. These and other incentives have made rare diseases faster and more accessible to pursue, resulting in an explosion of interest from pharma. Advancements in genomics and bioinformatics have improved our understanding of the mechanisms of previously neglected diseases such as malaria and TB. While these diseases have not received as much attention in the past due to complexities in drug discovery, advanced technology has provided the opportunity for targeted therapies with longer market exclusivity and higher prices. Companies such…
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